N-(3-methoxyphenyl)piperazine → HCID 68861650, compound

Participants

Reaction Steps

As described for Example 1f, 1-benzyl-4-[tert-butoxycarbonyl-(2,4-difluoro-benzyl)-amino]-pyrrolidine-2-carboxylic acid (60.0 mg, 0.134 mmol) was converted, using 1-(3-methoxy-phenyl)-piperazine instead of 2-piperazin-1-yl-benzonitrile, to the title compound (12.3 mg, 17.6%) as light yellow oil. MS m/e=521.4 [M+H]+.

Provenance & Evidence