3,5-Dichlorobenzoyl chloride → HCID 25121360, compound

Participants

Reaction Steps

As described for Example 89e, 2-[4-(4-amino-1-benzyl-pyrrolidine-2-carbonyl)-piperazin-1-yl]-benzonitrile (50.0 mg, 0.128 mmol) was converted, using 3,5-dichloro-benzoyl chloride instead of 2-chloro-benzoyl chloride, to the title compound (8.3 mg, 11.5%) as light yellow oil. MS m/e=562.2 [M+H]+.

Provenance & Evidence