HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride, 3,4,5-trimethoxy- → HCID 67548140, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride, 3,4,5-trimethoxy- | HCID 78282 | — |
| Reactant | HCID 57674252 | HCID 57674252 | — |
| Product | HCID 67548140 | HCID 67548140 | 17.9% |
Reaction Steps
As described for Example 89e, 2-[4-(4-amino-1-benzyl-pyrrolidine-2-carbonyl)-piperazin-1-yl]-benzonitrile (50.0 mg, 0.128 mmol) was converted, using 3,4,5-trimethoxy-benzoyl chloride instead of 2-chloro-benzoyl chloride, to the title compound (13.4 mg, 17.9%) as light yellow oil. MS m/e=583.7 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528136B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-79acacc7a97148abace5a32c2e552d07 |
| Source note | uspto-grants-2009_05 |