Acetonitrile → HCID 86607977, compound

Participants

Reaction Steps

To a solution of 1-(3,5-bis-trifluoromethyl-phenyl)-4-chloromethyl-5-methyl-1H-pyrazole (170 mg, 0.5 mmol) and (2-(5-hydroxy-indol-1-yl)-2-methyl-propionic acid (150 mg) in acetonitrile (3 mL) is added Cs2CO3 (325 mg, 1 mmol). The mixture is stirred at room temperature over night, quenched by water, extracted with ethyl acetate, dried over sodium sulfate. Concentration yields the crude product.

Provenance & Evidence