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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 49081Generated: October 25, 2026

2-Oxindole-5-carboxylic acid → 2-Oxo-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-2,3-dihydro-1H-indole-5-carboxylic acid

https://huagongshe.com/reaction/49081

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Oxindole-5-carboxylic acidHCID 2773318—
Reactant5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehydeHCID 22042092—
Product2-Oxo-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-2,3-dihydro-1H-indole-5-carboxylic acidHCID 69586861—

Reaction Steps

2-Oxo-2,3-dihydro-1H-indole-5-carboxylic acid was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06706709B2
Source datasetuspto-grants-2004_03
ORD IDord-7a52c9b7a340401d86afe2390c93eba8
Source noteuspto-grants-2004_03