Ethanol → HCID 9997363, compound

Participants

Reaction Steps

2-(Indol-3-ylmethylene)-malononitrile: A yellow suspension of malononitrile (0.114 g, 1.72 mmol), anhydrous EtOH (1.72 mL), indole-3-carboxaldehyde (0.250 g, 1.72 mmol), and piperidine (6.8 μL, 0.069 mmol) was heated to form a yellow solution. Within 5 min, a yellow precipitate was formed and the reaction mixture was cooled to room temperature over 15 min. The yellow precipitate was filtered and collected, yielding 0.250 g (75%) of the title compound as a yellow solid.

Provenance & Evidence