HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malononitrile → HCID 10088419, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malononitrile | HCID 8010 | — |
| Reactant | 3,5-Difluorobenzaldehyde | HCID 588160 | — |
| Reactant | 4-Hydroxy-1-methylindole | HCID 15825739 | — |
| Product | HCID 10088419 | HCID 10088419 | — |
Reaction Steps
The title compound was prepared from 4-hydroxy-1-methylindole (40 mg, 0.27 mmol), 3,5-difluorobenzaldehyde (38 mg, 0.27 mmol) and malononitrile (18 mg, 0.27 mmol) similar to Example 24 to yield 38 mg (42%) of white solids. 1H NMR (CDCl3): 7.07-7.03 (m, 2H), 6.76-6.73 (m, 3H), 6.68-6.62 (m, 1H), 6.57 (d, J=3.0 Hz, 1H), 4.83 (s, 1H), 4.72 (brs, 2H), 3.78 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528164B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-6d843c10b8d64740b0e42bab449a0dce |
| Source note | uspto-grants-2009_05 |