HuagongsheHuagongshe Chemistry Print Report · For research reference only
Malononitrile → HCID 10336490, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Malononitrile | HCID 8010 | — |
| Reactant | m-Formylbenzonitrile | HCID 90670 | — |
| Reactant | 4-Hydroxy-1-methylindole | HCID 15825739 | — |
| Product | HCID 10336490 | HCID 10336490 | — |
Reaction Steps
The title compound was prepared from 4-hydroxy-1-methylindole (40 mg, 0.27 mmol), 3-cyanobenzaldehyde (36 mg, 0.27 mmol) and malononitrile (18 mg, 0.27 mmol) similar to Example 24 to yield 87 mg (98%) of white solids. 1H NMR (CDCl3): 7.53-7.39 (m, 4H), 7.08-7.03 (m, 2H), 6.68 (d, J=8.4 Hz, 1H), 6.58 (d, J=3.3 Hz, 1H), 4.90 (s, 1H), 4.74 (brs, 2H), 3.79 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528164B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-569845268a044150922f389ed3c38afd |
| Source note | uspto-grants-2009_05 |