6-(4-Methoxy-phenyl)-1,3-dihydro-indol-2-one → 6-(4-Methoxy-phenyl)-3-[5-(2-morpholin-4-yl-ethoxy)-1H-indol-2-ylmethylene]-1,3-dihydro-indol-2-one

HRID 49086Notes

Reaction equation

HRID 49086 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:17]=[C:16]3[C:12]([CH2:13][C:14](=[O:18])[NH:15]3)=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.[N:19]1([CH2:25][CH2:26][O:27][C:28]2[CH:29]=[C:30]3[C:34](=[CH:35][CH:36]=2)[NH:33][C:32]([CH:37]=O)=[CH:31]3)[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[CH:17]=[C:16]3[C:12]([C:13](=[CH:37][C:32]4[NH:33][C:34]5[C:30]([CH:31]=4)=[CH:29][C:28]([O:27][CH2:26][CH2:25][N:19]4[CH2:24][CH2:23][O:22][CH2:21][CH2:20]4)=[CH:36][CH:35]=5)[C:14](=[O:18])[NH:15]3)=[CH:11][CH:10]=2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 107286906-(4-Methoxy-phenyl)-1,3-dihydro-indol-2-oneHCID 220421095-(2-morpholin-4-yl-ethoxy)-1H-indole-2-carbaldehyde

Product 1

HCID 695866866-(4-Methoxy-phenyl)-3-[5-(2-morpholin-4-yl-ethoxy)-1H-indol-2-ylmethylene]-1,3-dihydro-indol-2-one

Procedure

6-(4-Methoxy-phenyl)-1,3-dihydro-indol-2-one was condensed with 5-(2-morpholin-4-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Sources & evidence

ORD record
ord-47b00df6f2544c8daca5f62fb0375b43
Source dataset
uspto-grants-2004_03
Patent number
US06706709B2

Reaction notes

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