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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 49090Generated: October 25, 2026

N-methyl-2-oxoindoline-5-sulfonamide → 2-Oxo-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-2,3-dihydro-1H-indole-5-sulfonic acid methylamide

https://huagongshe.com/reaction/49090

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-oxoindoline-5-sulfonamideHCID 10176909—
Reactant5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehydeHCID 22042092—
Product2-Oxo-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-2,3-dihydro-1H-indole-5-sulfonic acid methylamideHCID 69344569—

Reaction Steps

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06706709B2
Source datasetuspto-grants-2004_03
ORD IDord-5836c456439d4c9992adf517389ca0b1
Source noteuspto-grants-2004_03