HCID 57675146, compound → N'-Acetyl-1-ethyl [methyl(tetrahydro-2H-pyran-4-yl)amino]-1H-pyrazolo[3,4-b]pyridine-5-carbohydrazide

HRID 490900Notes

Reaction equation

HRID 490900 reaction equation
C(N1C2=NC=C(C(O)=O)[C:11]([N:12](C)[CH:13]3[CH2:18][CH2:17][O:16][CH2:15][CH2:14]3)=C2C=N1)C.[C:23]([NH:26][NH:27][C:28]([C:30]1[C:31](NC2CCCC2)=[C:32]2[CH:38]=[N:37][N:36]([CH2:39][CH3:40])[C:33]2=[N:34][CH:35]=1)=[O:29])(=[O:25])[CH3:24]>>[C:23]([NH:26][NH:27][C:28]([C:30]1[CH:31]=[C:32]2[C:38]([N:12]([CH3:11])[CH:13]3[CH2:18][CH2:17][O:16][CH2:15][CH2:14]3)=[N:37][N:36]([CH2:39][CH3:40])[C:33]2=[N:34][CH:35]=1)=[O:29])(=[O:25])[CH3:24]

Participants

3

Procedure

Intermediate 53 was prepared from Intermediate 52 using an analogous method to that for Intermediate 4. LCMS showed MH+=361; TRET=1.91 min.

Workup

  1. customTRET=1.91 min.

Sources & evidence

ORD record
ord-ae183d4f4cec44af910e75f35448cf5f
Source dataset
uspto-grants-2009_05
Patent number
US07528148B2

Reaction notes

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