2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamide → 3-[5-(2-Morpholin-4-yl-ethoxy)-1H-indol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indol-5-sulfonic acid dimethylamide
Reaction equation
[CH3:1][N:2]([CH3:16])[S:3]([C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10](=[O:15])[CH2:9]2)(=[O:5])=[O:4].[N:17]1([CH2:23][CH2:24][O:25][C:26]2[CH:27]=[C:28]3[C:32](=[CH:33][CH:34]=2)[NH:31][C:30]([CH:35]=O)=[CH:29]3)[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>>[CH3:1][N:2]([CH3:16])[S:3]([C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10](=[O:15])[C:9]2=[CH:35][C:30]1[NH:31][C:32]2[C:28]([CH:29]=1)=[CH:27][C:26]([O:25][CH2:24][CH2:23][N:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1)=[CH:34][CH:33]=2)(=[O:5])=[O:4]Participants
3
Procedure
2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamide was condensed with 5-(2-morpholin-4-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.
Sources & evidence
- ORD record
- ord-ef1a9ab965dd415bab4b5dfa30a86446
- Source dataset
- uspto-grants-2004_03
- Patent number
- US06706709B2
Reaction notes
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