HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → n-Methyl-3-nitropyridin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 4-Chloro-3-nitropyridine | HCID 2735781 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | n-Methyl-3-nitropyridin-4-amine | HCID 556016 | — |
Reaction Steps
29.9 g of (9) were solubilised in 200 ml of hot ethanol; to the solution, brought to 0° C., were added slowly, dropwise, 103 ml of 35% aqueous methylamine. This was left stirring for 30 minutes and then the ethanol evaporated. The residue was crystallised in water giving 24 g of (10) in the form of clear yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528252B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-5376f6bb35d24b57a988330dc1d441ee |
| Source note | uspto-grants-2009_05 |