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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 49100Generated: October 25, 2026

Indole-3-Carboxaldehyde → 3-(1H-Indol-3-ylmethylene)-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide

https://huagongshe.com/reaction/49100

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndole-3-CarboxaldehydeHCID 10256—
ReactantN-methyl-2-oxoindoline-5-sulfonamideHCID 10176909—
Product3-(1H-Indol-3-ylmethylene)-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamideHCID 54255786—

Reaction Steps

5-Methylaminosulfonyl-2-oxindole was condensed with indole-3-carboxaldehyde to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06706709B2
Source datasetuspto-grants-2004_03
ORD IDord-8a51148f7dfa4f6dbda0536ac45ceff0
Source noteuspto-grants-2004_03