HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-(N-methylsulfamoyl)phenyloxy)-1-nitrobenzene → 4-(3-(N-methylsulfamoyl)phenyloxy)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-(N-methylsulfamoyl)phenyloxy)-1-nitrobenzene | HCID 23614572 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-(3-(N-methylsulfamoyl)phenyloxy)aniline | HCID 23137239 | 25.8% |
Reaction Steps
A slurry of 4-(3-(N-methylsulfamoyl)phenyloxy)-1-nitrobenzene (0.30 g) and 10% Pd/C (0.030 g) in EtOAc (20 mL) was stirred under an H2 atmosphere (balloon) overnight. The resulting mixture was filtered through a pad of Celite®. The filtrate was concentrated under reduced pressure. The residue was purified by column chromatography (30% EtOAcn70% hexane) to give 4-(3-(N-methylsulfamoyl)phenyloxy)aniline (0.070 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07528255B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-6f5902c342c349869242f1ac3c34092f |
| Source note | uspto-grants-2009_05 |