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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 49113Generated: October 29, 2026

Pyridine → HCID 7586589, compound

https://huagongshe.com/reaction/49113

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
Reactant2-MethoxyanilineHCID 7000—
Reactant2-oxo-2,3-dihydro-1H-indole-5-sulfonyl chlorideHCID 4962506—
SolventDichloromethaneHCID 6344—
ProductHCID 7586589HCID 758658937%

Reaction Steps

A solution of 5-chlorosulfonyl-2-oxindole (3 g), o-anisidine (1.8 mL) and pyridine (2.1 mL) in dichloromethane (20 mL) was stirred at room temperature for overnight at which time the red color solid was present. The solid was filtered, washed with ethanol and dried under vacuum to yield 1.5 g (37%) of 2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (2-methoxy-phenyl)-amide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06706709B2
Source datasetuspto-grants-2004_03
ORD IDord-5aff1de41939460a90672e3eb9cbb994
Source noteuspto-grants-2004_03