HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopyridine → 2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid pyridin-3-ylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopyridine | HCID 10009 | — |
| Reactant | 2-oxo-2,3-dihydro-1H-indole-5-sulfonyl chloride | HCID 4962506 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid pyridin-3-ylamide | HCID 69052510 | 38% |
Reaction Steps
A solution of 5-chlorosulfonyl-2-oxindole (3 g) and 3-aminopyridine (1.46 g) in pyridine (15 mL) was stirred at room temperature for overnight at which time the brown color solid was present. The precipitate was filtered, washed with ethanol and dried under vacuum to yield 1.4 g (38%) of 2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid pyridin-3-ylamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06706709B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-a448c9033e3b427486cb7abc44de8ab3 |
| Source note | uspto-grants-2004_03 |