HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(9-Fluorenylmethoxycarbonyl)-O-tert-butylthreonine → Fmoc-Thr-OTce
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(9-Fluorenylmethoxycarbonyl)-O-tert-butylthreonine | HCID 6364643 | — |
| Reactant | Fmoc-Ser-OTce | HCID 10939458 | — |
| Product | Fmoc-Thr-OTce | HCID 10994354 | 68% |
Reaction Steps
According to the procedure used for the synthesis of Fmoc-Ser-OTce, Fmoc-Thr(OtBu)-OH (1 g, 2.5 mmol) provided Fmoc-Thr-OTce (0.81 g, 1.7 mmol, 68% overall yield for two steps).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07531506B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-ed601c4c828d4da998c62a8cb0ec6efe |
| Source note | uspto-grants-2009_05 |