HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 491288Generated: November 1, 2026
Potassium Carbonate → HCID 11740008, compound
https://huagongshe.com/reaction/491288
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloro-4-(trifluoromethyl)pyrimidine | HCID 2773912 | — |
| Reactant | HCID 178418879 | HCID 178418879 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 11740008 | HCID 11740008 | — |
Reaction Steps
2-Chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine is dissolved in dimethyl formamide. Potassium carbonate and 2-chloro-4-trifluoromethyl-pyrimidine are added and the reaction mixture is stirred at about 80° C. overnight. It is obtained 2-[4-(2-chloro-pyridin-4- ylethynyl)-2-methyl-imidazol-1-yl]-4-trifluoromethyl-pyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07531529B2 |
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| Source dataset | uspto-grants-2009_05 |
|---|
| ORD ID | ord-28a4bce1fc624086814ad953059043f7 |
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| Source note | uspto-grants-2009_05 |
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