2,4-Difluorophenylboronic acid → HCID 86595312, compound

HRID 491307Notes

Reaction equation

HRID 491307 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.[F:16][C:17]1[CH:22]=[C:21]([F:23])[CH:20]=[CH:19][C:18]=1B(O)O>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[N:13]([C:20]3[CH:19]=[CH:18][C:17]([F:16])=[CH:22][C:21]=3[F:23])[CH:14]=2)[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 27343342,4-Difluorophenylboronic acidHCID 178418879HCID 178418879, compound

Product 1

HCID 86595312HCID 86595312, compound

Procedure

The title compound, MS: m/e=330.4 (M+H+), was prepared in accordance with the general method of example 7 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2,4-difluorobenzene boronic acid.

Sources & evidence

ORD record
ord-7a58695919f140bb97046378c8c12549
Source dataset
uspto-grants-2009_05
Patent number
US07531529B2

Reaction notes

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