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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 491313Generated: October 28, 2026

3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) → 2-Chloro-4-[1-(3-chloro-4-fluoro-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine

https://huagongshe.com/reaction/491313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride)HCID 2734660—
ReactantHCID 178418879HCID 178418879—
Product2-Chloro-4-[1-(3-chloro-4-fluoro-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridineHCID 86595317—

Reaction Steps

The title compound, MS: m/e=347.2 (M+H+), was prepared in accordance with the general method of example 7 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 3-chloro-4-fluoro-benzene boronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07531529B2
Source datasetuspto-grants-2009_05
ORD IDord-22d9dc8f86b9438385fea84815d20493
Source noteuspto-grants-2009_05