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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 491327Generated: October 31, 2026

Trimethylsilylacetylene → 2-Chloro-5-(2-methyl-4-trimethylsilanylethynyl-imidazol-1-yl)-pyridine

https://huagongshe.com/reaction/491327

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethylsilylacetyleneHCID 66111—
Reactant2-Chloro-5-(4-iodo-2-methyl-imidazol-1-yl)-pyridineHCID 86012439—
Product2-Chloro-5-(2-methyl-4-trimethylsilanylethynyl-imidazol-1-yl)-pyridineHCID 86595325—

Reaction Steps

The title compound, MS: m/e=290.6 (M+H+), was prepared in accordance with the general method of example B, step 1, from 2-chloro-5-(4-iodo-2-methyl-imidazol-1-yl)-pyridine and trimethylsilylacetylen.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07531529B2
Source datasetuspto-grants-2009_05
ORD IDord-9b2056ff6c414aeaa8c3beb33e76f088
Source noteuspto-grants-2009_05