HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Bromoethyl)benzoic acid → (3-Bromomethyl-phenyl)-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Bromoethyl)benzoic acid | HCID 104068 | — |
| Reactant | 2-(3-(Bromomethyl)phenyl)acetic acid | HCID 10376509 | — |
| Product | (3-Bromomethyl-phenyl)-acetic acid methyl ester | HCID 10014651 | — |
Reaction Steps
According to the procedures described in the synthesis method of Intermediate ia-01, 2-[3-(bromomethyl)phenyl]acetic acid (500 mg) synthesized according to the procedures described in International Patent Publication WO00/03980 was used instead of 4-(2-bromoethyl)benzoic acid, and the material was reacted and treated to obtain the title compound (Intermediate il-01, 471 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07531533B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-e81e3e2667644b58b5b66d36e6efaf1e |
| Source note | uspto-grants-2009_05 |