Morpholine, 4-(chloroacetyl)- → HCID 68879318, compound

HRID 491450Notes

Reaction equation

HRID 491450 reaction equation
[Cl:1][CH2:2][C:3]([N:5]1[CH2:10][CH2:9][O:8][CH2:7][CH2:6]1)=[O:4].Cl.[CH3:12][O:13][C:14]1[CH:15]=[C:16]([C:22]2[C@@H:31]3[C@@H:26]([CH2:27][CH:28]=[CH:29][CH2:30]3)[C:25](=[O:32])[N:24]([CH:33]3[CH2:38][CH2:37][N:36](CC4C=C5C(C=CC(=O)O5)=CC=4)[CH2:35][CH2:34]3)[N:23]=2)[CH:17]=[CH:18][C:19]=1[O:20][CH3:21]>>[ClH:1].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([C:22]2[C@@H:31]3[C@@H:26]([CH2:27][CH:28]=[CH:29][CH2:30]3)[C:25](=[O:32])[N:24]([CH:33]3[CH2:38][CH2:37][N:36]([CH2:2][C:3]([N:5]4[CH2:10][CH2:9][O:8][CH2:7][CH2:6]4)=[O:4])[CH2:35][CH2:34]3)[N:23]=2)[CH:17]=[CH:18][C:19]=1[O:20][CH3:21]

Participants

3

Reactant 2

HCID 74040Morpholine, 4-(chloroacetyl)-HCID 86601097HCID 86601097, compound

Product 1

HCID 68879318HCID 68879318, compound

Procedure

Prepared from 4-(2-chloroacetyl)morpholine and starting compound A1 as described for compound 18. M.p. 159-162° C.

Sources & evidence

ORD record
ord-0f25b1b0f4dd4941bfc869d7fab0013c
Source dataset
uspto-grants-2009_05
Patent number
US07531540B2

Reaction notes

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