反应详情

10 g (42 mmol) of diethyl 2-methylbenzylphosphonate were dissolved in 60 ml of trimethyl phosphate and the solution was introduced into a flask protected from light and moisture. 16 g (0.05 mol) of Br2 were added dropwise, while stirring. The mixture was stirred at 90° C. for 15 hours and, after cooling, was diluted with 100 ml of water and extracted three times with 100 ml of n-hexane each time. The organic phase wa dried, concentrated and distilled.

1. additionthe solution was introduced into a flask
2. stirringThe mixture was stirred at 90° C. for 15 hours
3. temperatureafter cooling
4. extractionextracted three times with 100 ml of n-hexane each time
5. customThe organic phase wa dried
6. concentrationconcentrated
7. distillationdistilled