HCID 57678401, compound → HCID 57678416, compound

HRID 491506Notes

Reaction equation

HRID 491506 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[C:5]([C:10](O)([CH3:12])[CH3:11])=[C:4]([O:14][CH3:15])[CH:3]=1>C(Cl)(Cl)Cl>[C:10]([C:5]1[C:6]([O:8][CH3:9])=[CH:7][C:2]([NH2:1])=[CH:3][C:4]=1[O:14][CH3:15])([CH3:12])=[CH2:11]

Participants

3

Reactant 1

HCID 57678401HCID 57678401, compound

Product 1

HCID 57678416HCID 57678416, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A solution of 2-(4-Amino-2,6-dimethoxy-phenyl)-propan-2-ol (2.2 g, 10.4 mmol) in chloroform (100 mL) was refluxed overnight. The cooled reaction mixture was concentrated under reduced pressure to yield 4-Isopropenyl-3,5-dimethoxy-phenylamine, which was used directly in the following step.

Workup

  1. customThe cooled reaction mixture
  2. concentrationwas concentrated under reduced pressure

Sources & evidence

ORD record
ord-462029a8d4f346d1ad5fff9ee4b4e291
Source dataset
uspto-grants-2009_05
Patent number
US07531547B2

Reaction notes

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