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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 491567Generated: October 25, 2026

2,4-Difluoroacetophenone → 6-(2,4-Difluorophenyl)nicotinic acid

https://huagongshe.com/reaction/491567

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluoroacetophenoneHCID 67770—
Reactant6-(4-Fluorophenyl)nicotinic acidHCID 22730186—
Product6-(2,4-Difluorophenyl)nicotinic acidHCID 24729985—

Reaction Steps

The title compound was prepared from 2′,4′-difluoroacetophenone using the procedures outlined for 6-(4-fluorophenyl)nicotinic acid (D1-D3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07531558B2
Source datasetuspto-grants-2009_05
ORD IDord-695bcc4cb9694d79be18d195c1f8a621
Source noteuspto-grants-2009_05