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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 491568Generated: October 25, 2026

1-(3,4-Difluorophenyl)ethan-1-one → 6-(3,4-Difluorophenyl)pyridine-3-carboxylic acid

https://huagongshe.com/reaction/491568

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3,4-Difluorophenyl)ethan-1-oneHCID 123052—
Reactant6-(4-Fluorophenyl)nicotinic acidHCID 22730186—
Product6-(3,4-Difluorophenyl)pyridine-3-carboxylic acidHCID 52984092—

Reaction Steps

The title compound was prepared from 3′,4′-difluoroacetophenone using the procedures outlined for 6-(4-fluorophenyl)nicotinic acid (D1-D3).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07531558B2
Source datasetuspto-grants-2009_05
ORD IDord-cdc2fe2ac3ce4e93b39da8a16d8ea2ba
Source noteuspto-grants-2009_05