HCID 21961470, compound → HCID 21959569, compound

HRID 491627Notes

Reaction equation

HRID 491627 reaction equation
[CH3:1][N:2]1[CH2:7][CH:6]=[C:5]([C:8]([CH3:19])([C:10]2[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][CH:11]=2)[CH3:9])[CH2:4][CH2:3]1>CCO.[Pd]>[CH3:19][C:8]([C:10]1[CH:11]=[CH:12][C:13]([NH2:16])=[CH:14][CH:15]=1)([CH:5]1[CH2:4][CH2:3][N:2]([CH3:1])[CH2:7][CH2:6]1)[CH3:9]

Participants

4

Reactant 1

HCID 21961470HCID 21961470, compound

Product 1

HCID 21959569HCID 21959569, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

1-Methyl-4-[1-methyl-1-(4-nitro-phenyl)-ethyl]-1,2,3,6-tetrahydro-pyridine (Step B) was hydrogenated with Pd/C 10% at atmospheric pressure at RT in EtOH to yield the title compound.

Sources & evidence

ORD record
ord-06b1674b4307472ebd80e0189c74c5f6
Source dataset
uspto-grants-2009_05
Patent number
US07531553B2

Reaction notes

Loading…