反应详情

N-[3-(3,4-Dinitro-phenoxy)-phenyl]-acetamide (Step A, 0.4 g, 1.3 mmol, 1.0 eq.) was dissolved in MeOH (10 mL) and the atmosphere was replaced by argon. A catalytic amount of 10% Pd/C was added and the argon was replaced by a H2 atmosphere. The mixture was stirred for 16 h at RT at balloon pressure. The Pd/C was filtered and the obtained N-[3-(3,4-diamino-phenoxy)-phenyl]-acetamide was used crude in the next step. MS m/z=259.1 (M+H)+Calc'd for C14H15N3O2: 257.29.

1. filtrationThe Pd/C was filtered