HCID 17755617, compound → HCID 11341153, compound

Participants

Reaction Steps

4-{2-Chloro-5-[5-(2-methylcarbamoyl-pyridin-4-yloxy)-benzoxazol-2-ylamino]-phenoxymethyl}-piperidine-1-carboxylic acid tert-butyl ester was dissolved in TFA (2 mL). After stirring for 2 h at RT, the mixture was concentrated in vacuo and taken up into EtOAc and washed with NaOH, then NaHCO3 (sat). The organic layer was dried with Na2SO4, filtered and evaporated. The title compound was obtained after purification by prepatory HPLC as a white solid. MS(MH+)=508.1; Calc'd 507.17 for C26H26ClN5O4.

Provenance & Evidence