HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 178501119, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 178511262 | HCID 178511262 | — |
| Product | HCID 178501119 | HCID 178501119 | — |
Reaction Steps
Trans-4-(aminomethyl)cyclohexanecarboxylic acid (6.29 g) is suspended in methanol (32 ml) and to the suspension is added dropwise thionyl chloride (6 ml) under ice-cooling. The reaction solution is warmed to room temperature, stirred overnight and concentrated under reduced pressure to dryness, which provides methyl trans-4-(aminomethyl)cyclohexanecarboxylate hydrochloride (8.69 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07531537B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-265de67f427e472fad21ee7426d900fb |
| Source note | uspto-grants-2009_05 |