HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 491864Generated: October 30, 2026
Dimethylformamide dimethyl acetal → Dimethyl-[2-(5-nitro-2-phenoxy-pyridin-4-yl)-vinyl]-amine
https://huagongshe.com/reaction/491864
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | 4-Methyl-5-nitro-2-phenoxy-pyridine | HCID 57678357 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Dimethyl-[2-(5-nitro-2-phenoxy-pyridin-4-yl)-vinyl]-amine | HCID 86616325 | — |
Reaction Steps
A mixture of 4-methyl-5-nitro-2-phenoxy-pyridine (0.2 g, 0.86 mmol) and N,N-dimethylformamide dimethyl acetal (0.13 g, 1.1 mmol) in DMF (1 mL) was stirred at 130° C. for 1 hr, then cooled and concentrated to yield crude dimethyl-[2-(5-nitro-2-phenoxy-pyridin-4-yl)-vinyl]-amine as a syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07531545B2 |
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| Source dataset | uspto-grants-2009_05 |
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| ORD ID | ord-9c87f7c911d24091a2f87c254d60c561 |
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| Source note | uspto-grants-2009_05 |
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