HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pentanenitrile, 4,4-dimethyl-3-oxo- → methyl 4-(5-amino-3-tert-butyl-1H-pyrazol-1-yl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pentanenitrile, 4,4-dimethyl-3-oxo- | HCID 108871 | — |
| Reactant | Methyl 4-hydrazinylbenzoate | HCID 408928 | — |
| Product | methyl 4-(5-amino-3-tert-butyl-1H-pyrazol-1-yl)benzoate | HCID 2973426 | — |
Reaction Steps
Methyl 4-(3-tert-butyl-5-amino-1H-pyrazol-1-yl)benzoate (3.67 mmol) was prepared from methyl 4-hydrazinobenzoate and pivaloylacetonitrile by the procedure of Regan, et al., J. Med. Chem., 45, 2994 (2002).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07531566B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-a06d8160262f4300807e3c2991c0179b |
| Source note | uspto-grants-2009_05 |