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HRID4920

反应详情

EQUATION

反应方程式

HRID 4920 的结构方程式

REACTANTS

反应物

2
结构：NCCCCN1CCN(c2ncccn2)CC1
HCID12840705

4-[4-(Pyrimidin-2-yl)piperazin-1-yl]butan-1-amine

C12H21N5

结构：CC1(C)C2CCC1C(=O)OC2=O
HCID19797203

8,8-Dimethyl-3-oxabicyclo[3.2.1]octane-2,4-dione

C9H12O3

PRODUCTS

生成物

1
结构：CC1(C)C2CCC1C(=O)N(CCCCN1CCN(c3ncccn3)CC1)C2=O
HCID14097164

未命名化合物

收率 32%

PROCEDURE

实验过程

Following substantially the procedure of Example 1, 0.54 g (2.34 mmol) of 1-(4-aminobutyl)-4-(2-pyrimidinyl) piperazine was reacted with 0.36 g (2.14 mmol) of 8,8-dimethyl-3-oxabicyclo[3.2.1]octan-2,4-dione. The product was chromatographed on silica gel, eluting with dichloromethane/methanol (96:4), to give 0.25 g (32% yield) of the title compound.

WORKUP

后处理

  1. customThe product was chromatographed on silica gel
  2. washeluting with dichloromethane/methanol (96:4)