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3-Nitrobenzamide → 3-Nitrobenzylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Nitrobenzamide | HCID 12576 | — |
| 反応物 | Aluminium lithium hydride | HCID 21226445 | — |
| 生成物 | 3-Nitrobenzylamine | HCID 122722 | — |
反応手順
Commercially available 3-nitrobenzamide is reduced with LAH under standard conditions to afford (3-nitrophenyl)methanamine, which is reacted with succinic anhydride under standard conditions to afford 1-(3-nitrobenzyl)pyrrolidine-2,5-dione. This material is reduced at the nitro group and oxidized to afford 1-(3-hydrazinobenzyl)pyrrolidine-2,5-dione.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07531566B2 |
| 出典データセット | uspto-grants-2009_05 |
| ORD ID | ord-6bdfe517728348d49aa48d175d29dc41 |
| 出典メモ | uspto-grants-2009_05 |