Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonium Acetate → 1-Amino-5-(2,5-difluorophenyl)cyclohexan-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonium Acetate | HCID 517165 | — |
| 반응물 | 5-(2,5-Difluorophenyl)cyclohexane-1,3-dione | HCID 17823917 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-Amino-5-(2,5-difluorophenyl)cyclohexan-3-one | HCID 17823918 | 92.1% |
반응 단계
A solution of 5-(2,5-difluorophenyl)cyclohexane-1,3-dione (4.0 g) and ammonium acetate (4.1 g) in ethanol (60 ml) was heated under reflux for 12 hours. The reaction mixture was concentrated under reduced pressure, and the residue was washed with water and dried to obtain 1-amino-5-(2,5-difluorophenyl)cyclohexan-3-one (3.7 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06706732B1 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-127ad5525e15414fa8391ce0006812bd |
| 출처 메모 | uspto-grants-2004_03 |