Sarcosine → HCID 24798585, compound

Participants

Reaction Steps

Following the general procedure for the synthesis of acyloxyalkyl carbamates, sarcosine (0.123 g, 1.3 mmol) and (2,5-dioxoazolidinyloxycarbonyloxy)methyl 2-methylpropanoate (0.300 g, 1.1 mmol) were reacted to provide 0.138 g (51.3% yield) of the title compound (46) as a colorless semi-solid material after work-up and mass-guided preparative HPLC purification. 1H NMR (CD3OD, 400 MHz): δ=5.78 (d, 2H), 4.12 (d, 3H), 3.02 (d, 3H), 2.62 (m, 1H), 1.2 (t, 6H). MS (ESI) m/z 256.05 (M+Na)+.

Provenance & Evidence