huagongshe.com
HRID4921

反应详情

EQUATION

反应方程式

HRID 4921 的结构方程式

REACTANTS

反应物

2
结构：CC12CCC(C)(C1)C(=O)OC2=O
HCID12530271

未命名化合物

结构：NCCCCN1CCN(c2ncccn2)CC1
HCID12840705

4-[4-(Pyrimidin-2-yl)piperazin-1-yl]butan-1-amine

C12H21N5

PRODUCTS

生成物

1
结构：CC12CCC(C)(C1)C(=O)N(CCCCN1CCN(c3ncccn3)CC1)C2=O
HCID14097166

未命名化合物

收率 21%

PROCEDURE

实验过程

Following substantially the procedure of Example 1, 4.2 g (17.8 mmol) of 1-(4-aminobutyl)-4-(2-pyrimidinyl) piperazine was reacted with 2.99 g (17.8 mmol) of 1,5-dimethyl-3-oxabicyclo[3.2.1]octan-2,4-dione. The product was chromatographed on silica gel, eluting with dichloromethane/methanol (96:4), to give 1.4 g (21% yield) of the title compound.

WORKUP

后处理

  1. customThe product was chromatographed on silica gel
  2. washeluting with dichloromethane/methanol (96:4)