Oxalyl chloride → HCID 86596413, compound

Participants

Reaction Conditions

Reaction Steps

0.6 cm3 (6.88 mmol) of oxalyl chloride is added to a suspension, cooled to a temperature in the region of 5° C., of 0.74 g (2.28 mmol) of 3-carboxy-1-(quinol-8-yl)-1H-indole hydrochloride in 15 cm3 of dichloromethane under an argon atmosphere. After stirring at a temperature in the region of 22° C. for 15 hours, the reaction mixture is concentrated to dryness under reduced pressure (2.7 kPa) to give 0.9 g of 3-chlorocarbonyl-1-(quinol-8-yl)-1H-indole hydrochloride in the form of a yellow solid which is used directly in the following step.

Provenance & Evidence