HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 6-[4-(2-Benzylamino-2-methyl-propyl)-phenoxy]-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 6-[4-(2-Amino-2-methyl-propyl)phenoxy]-nicotinamide | HCID 15429143 | — |
| Product | 6-[4-(2-Benzylamino-2-methyl-propyl)-phenoxy]-nicotinamide | HCID 59730070 | — |
Reaction Steps
Using a method similar to example 2, using 6-[4-(2-amino-2-methyl-propyl)phenoxy]-nicotinamide and benzyl bromide gives the title product: HPLC (30/70 to 90/10 ACN/(0.1% TFA in water) Zorbax SB-Phenyl Column 4.6 mm×15 cm×5 micron: Retention time: 3.96 minutes, Purity: 100%; mass spectrum (ion spray): m/z=376.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07531557B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-e86a7b884f6e4e51bb4d8ca81aa391a6 |
| Source note | uspto-grants-2009_05 |