Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 492343Generated: October 31, 2026

4-Hydroxybenzaldehyde → 3-Chloro-4-(4-formylphenoxy)benzonitrile

https://huagongshe.com/reaction/492343

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-HydroxybenzaldehydeHCID 126—
Reactant3-Chloro-4-fluorobenzonitrileHCID 145525—
Product3-Chloro-4-(4-formylphenoxy)benzonitrileHCID 568514251.91%

Reaction Steps

The above compound is prepared by nucleophilic displacement reaction of 4-hydroxy benzaldehyde and 3-chloro-4-fluorobenzonitrile under basic conditions as described in Example 243, step 1.91% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07531557B2
Source datasetuspto-grants-2009_05
ORD IDord-4836563750ed498e9e4aefad19daaaa5
Source noteuspto-grants-2009_05