cis-1,3-Cyclopentanedicarboxylic acid → 1,3-Cyclopentanedicarboxylic anhydride

Participants

Reaction Steps

A solution of 1.63 g of cis-cyclopentane-1,3-dicarboxylic acid in 8.2 ml of acetic anhydride was heated in an oil bath at ca. 100° C. for 45 minutes. The excess acetic anhydride and acetic acid were removed by evaporation in vacuo to give a solid which was triturated under diethyl ether. This afforded 1.14 g (79% yield) of the title anhydride.

Provenance & Evidence