HCID 23153418, compound → HCID 23152996, compound

Participants

Reaction Steps

2-{[4-(4-Hydroxypiperidin-1-yl)piperidin-1-yl]carbonylamino}-4-(4-nitrophenoxy)pyridine (243 mg) was dissolved in tetrahydrofuran (25 ml). After then adding 20% palladium hydroxide-carbon (140 mg), the mixture was stirred overnight under a hydrogen atmosphere. The catalyst was filtered and washed with tetrahydrofuran. The filtrate and the washings were then combined and concentrated under reduced pressure, and the resultant residue was dried under reduced pressure to provide the title compound (214 mg) as pale yellow powder.

Provenance & Evidence