Dimethyl Sulfate → HCID 86624072, compound

HRID 493013Notes

Reaction equation

HRID 493013 reaction equation
[CH3:1][N:2]([CH3:23])[C:3]1[CH:22]=[CH:21][C:6](/[CH:7]=[C:8]2/[C:9](=[O:20])[N:10]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)[N:11]=[C:12]/2[CH3:13])=[CH:5][CH:4]=1.[S:24]([O:29]C)([O:27][CH3:28])(=[O:26])=[O:25]>CC(C)=O>[CH3:28][O:27][S:24]([O-:29])(=[O:26])=[O:25].[CH3:23][N:2]([CH3:1])[C:3]1[CH:4]=[CH:5][C:6](/[CH:7]=[C:8]2\[C:12]([CH3:13])=[N:11][N:10]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N+:15]=3[CH3:28])[C:9]\2=[O:20])=[CH:21][CH:22]=1

Participants

4

Reactant 2

HCID 6497Dimethyl SulfateHCID 68826834HCID 68826834, compound

Product 1

HCID 86624072HCID 86624072, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

In 40 ml of acetone, 0.4 g (1.3 mmol) of (4E)-4-[4-(dimethylamino)benzylidene]-5-methyl-2-(2-pyridinyl)-2,4-dihydro-3H-pyrazol-3-one and 1.66 g (13.06 mmol) of dimethyl sulfate are stirred under reflux for one hour. The precipitated product is filtered off with suction, washed with acetone and dried under reduced pressure.

Workup

  1. temperatureunder reflux for one hour
  2. filtrationThe precipitated product is filtered off with suction
  3. washwashed with acetone
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-a5c47664ef9148e3a85263847d476e96
Source dataset
uspto-grants-2009_05
Patent number
US07534273B2

Reaction notes

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