反应详情

In 50 ml of chloroform was dissolved 8.63 g (57.5 mmol) of 4-n-propylbenzyl alcohol synthesized in the step (ii), and 8.10 g (68.1 mmol) of thionyl chloride was added to the mixture. The mixture was subjected to reaction at a room temperature for 24 hours. After the completion of the reaction, the chloroform phase was washed successively with an aqueous solution of sodium hydrogencarbonate and water. Chloroform was removed from the chloroform phase to give 9.40 g (55.8 mmol) of 4-n-propylbenzylchloride.

1. additionwas added to the mixture
2. customThe mixture was subjected to reaction at a room temperature for 24 hours
3. customAfter the completion of the reaction
4. washthe chloroform phase was washed successively with an aqueous solution of sodium hydrogencarbonate and water
5. customChloroform was removed from the chloroform phase