Trifluoroacetate → HCID 11654812, compound

HRID 493087Notes

Reaction equation

HRID 493087 reaction equation
C([O:8][C:9]1[CH:10]=[C:11]([CH:20]([OH:26])[CH:21](OCC)O)[C:12]2[O:17][CH2:16][C:15](=[O:18])[NH:14][C:13]=2[CH:19]=1)C1C=CC=CC=1.[NH2:27][C:28]([CH3:42])([CH3:41])[CH2:29][CH2:30][N:31]1[C:35]2[CH:36]=[CH:37][CH:38]=[CH:39][C:34]=2[O:33][C:32]1=[O:40].FC(F)(F)C([O-])=O>>[CH3:42][C:28]([NH:27][CH2:21][CH:20]([C:11]1[C:12]2[O:17][CH2:16][C:15](=[O:18])[NH:14][C:13]=2[CH:19]=[C:9]([OH:8])[CH:10]=1)[OH:26])([CH3:41])[CH2:29][CH2:30][N:31]1[C:35]2[CH:36]=[CH:37][CH:38]=[CH:39][C:34]=2[O:33][C:32]1=[O:40]

Participants

4

Reactant 3

HCID 84468TrifluoroacetateHCID 574358383-(3-amino-3-methyl-butyl)-3H-benzoxazol-2-oneHCID 671880308-(2-Ethoxy-1,2-dihydroxyethyl)-6-(phenylmethoxy)-2H-1,4-benzoxazin-3(4H)-one

Product 1

HCID 11654812HCID 11654812, compound

Procedure

This is prepared according to General Method 1 from 357 mg (1 mmol) 6-benzyloxy-8-(2-ethoxy-1,2-dihydroxy-ethyl)-4H-benzo[1,4]oxazin-3-one and 220 mg (1 mmol) 3-(3-amino-3-methyl-butyl)-3H-benzoxazol-2-one. Yield: 227 mg (42%, trifluoroacetate); mass spectroscopy: [M+H]+=428.

Workup

  1. customThis is prepared

Sources & evidence

ORD record
ord-c7f721339cc046a0a83284fd7377855a
Source dataset
uspto-grants-2009_05
Patent number
US07534789B2

Reaction notes

Loading…