3-Aminopyrrolidine → HCID 22036446, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 4, Step 2, starting from 2-chloro-3-(2-phenoxyethoxy)pyrazine (150 mg, 0.60 mmol; from Example 1, Step 1) and 3-aminopyrrolidine (270 mg, 3.13 mmol) with the exception that a final extraction step between EtOAc and 5% aqueous NaOH was carried out. This gave 121 mg (67%) of the title product. Anal. (C16H19N4O2) C, H; N: calcd, 18.65; found, 18.0.

Provenance & Evidence