HRID49333

反应详情

EQUATION

反应方程式

REACTANTS

反应物

$结构：CC/C(=C\CO)c1ccc(COc2ccc(CO[Si](C)(C)C(C)(C)C)c(CO[Si](C)(C)C(C)(C)C)c2)s1$

HCID69825143

未命名化合物

PRODUCTS

生成物

$结构：CC/C(=C\C=O)c1ccc(COc2ccc(CO[Si](C)(C)C(C)(C)C)c(CO[Si](C)(C)C(C)(C)C)c2)s1$

HCID88011784

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID178418406

未命名化合物

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

2.74 g (5.1 mmol) of (E)-3-{5-[3,4-bis(tert-butyldimethylsilanyloxymethyl)phenoxymethyl]-2-thienyl}pent-2-en-1-ol are dissolved in 80 mL of dichloromethane and placed under a nitrogen atmosphere. 4.45 g (51 mmol) of manganese dioxide are added and the medium is stirred for 14 hours. After filtration and then evaporation, a yellow oil is obtained. The crude product (2.9 g) is the expected aldehyde, obtained in a quantitative yield.

WORKUP

后处理

filtrationAfter filtration
customevaporation
customa yellow oil is obtained
customobtained in a quantitative yield

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f532658f0633418d9484d7cfb4c99f62
来源数据集: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06706725B1
来源说明: uspto-grants-2004_03

反应 SMILES

[Si:1]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:26]=[CH:27][C:28]=1[CH2:29][O:30][Si:31]([C:34]([CH3:37])([CH3:36])[CH3:35])([CH3:33])[CH3:32])[O:13][CH2:14][C:15]1[S:19][C:18](/[C:20](/[CH2:24][CH3:25])=[CH:21]/[CH2:22][OH:23])=[CH:17][CH:16]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]>ClCCl.[O-2].[O-2].[Mn+4]>[Si:1]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:26]=[CH:27][C:28]=1[CH2:29][O:30][Si:31]([C:34]([CH3:35])([CH3:37])[CH3:36])([CH3:32])[CH3:33])[O:13][CH2:14][C:15]1[S:19][C:18](/[C:20](/[CH2:24][CH3:25])=[CH:21]/[CH:22]=[O:23])=[CH:17][CH:16]=1)([C:4]([CH3:6])([CH3:5])[CH3:7])([CH3:3])[CH3:2]