Sodium Methoxide → HCID 86608748, compound

HRID 493412Notes

Reaction equation

HRID 493412 reaction equation
Br[C:2]([CH3:19])([CH3:18])[C:3]([C:5]1[CH:10]=[CH:9][C:8]([S:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:7][CH:6]=1)=[O:4].[CH3:20][O-:21].[Na+]>CO>[CH3:20][O:21][C:3]1([C:5]2[CH:10]=[CH:9][C:8]([S:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[CH:7][CH:6]=2)[C:2]([CH3:19])([CH3:18])[O:4]1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 67073622HCID 67073622, compound

Product 1

HCID 86608748HCID 86608748, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

3 g (0.0551 mol) of 2-bromo-2-methyl-1-(4-phenylsulphanyl-phenyl)-propan-1-one were dissolved in 30 ml of methanol. 1.79 ml of a 30% sodium methylate solution in methanol at room temperature were added. After 15′ the solution was evaporated and the product used without further purification in the following reaction.

Workup

  1. customAfter 15′ the solution was evaporated
  2. customthe product used without further purification in the following reaction

Sources & evidence

ORD record
ord-4a61e073c47244869e14c0d15a9b79e7
Source dataset
uspto-grants-2009_05
Patent number
US07534880B2

Reaction notes

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